| 1828 |
 |  | A small dispensary company which later takes the A S Watson name opens in Guangzhou. |
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| 1841 |
| | The dispensary moves its operations to Hong Kong and is renamed as HK Dispensary. |
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1863 |
| | Hongkong and Whampoa Dock Company (HWD) is established to acquire docks and repair yards at Whampoa, on the Pearl River in China, and at the then newly constructed dry docks at Aberdeen on Hong Kong Island. |
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| | The HK Dispensary becomes A S Watson. |
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1877 |
| | A young Briton, John Duflon Hutchison joins Hong Kong's small community of expatriate merchants in the employment of Robert Walker and Company. Before long he is able to take over the company, thus forming John D Hutchison and Company Ltd and the early roots of the Hutchison names are formed. |
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1883 |
| | A.S. Watson expands overseas to the Philippines and China; establishes a pharmacy and a soft drink factory (1884) in Manila. |
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1903 |
| | Watson's Water is established to provide the purest and the healthiest water to consumers in Hong Kong and the Mainland China. |
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